There have been historical stigmatics that were known to have faked wounds, such as Magdalena de la Cruz (1487–1560), who admitted the fraud.
Similarly self-inflicted wounds can be associated with certain mental illnesses. Some people who fake stigmata suffer from Munchausen syndrome which is characterised by an intense desire for attention. People with Munchausen hurt themselves or fake an illness hoping to end up in a hospital where they can enjoy attention and care.
People also fake stigmata knowing that some who had stigmata were declared holy by the Pope. In this way they try to gain recognition.
Skeptics also point out that stigmata have appeared on hands in some cases, and wrists in others . It is unknown whether crucifixion involved nails being driven through the hands or wrists. It has been proven in several studies that the hands would be unable to support the necessary weight, so many advocate the wrist theory; traditional art, however, often presents the opposite view. A New study and a documentory on the National Geographic channel "Quest for Truth: The Crucifixion,", have shown that a person can be supended by the wrists. As the ankels are nailed to the side of the cross producing little strain on the wrists. They also say the palms are a likely place for the nails as it would casue the maximum abount of pain and trauma. a brief news article on the experiment and the documentory can be found here:
http://www.msnbc.msn.com/id/7291066/#storyContinued and the national geographic site page is here:
http://channel.nationalgeographic.com/channel/questfortruth/
Similarly, no case of stigmata is known to have occurred before the thirteenth century, when the crucified Jesus became a standard icon of Christianity in the west .
Some believe that the condition can be 'explained' by 'frontier science' such as with the unexplained phenomena of the mind exerting physical effects on the body. There have been claims that non-religious people under deep hypnosis, when told that they have a crown of thorns on their head cutting into their flesh (in the manner that it happened to Christ), have had bleeding welts appear on their foreheads even when nothing has come into contact with the skin. Thus if this is true, the effects have been inflicted by the mind, onto the body. Other accounts of this strong mind-body connection have been observed and documented in experiments such as the case in which heart disease patients were administered a placebo pill, but told that it was a new 'super-medicine', and their conditions noticeably improved. It is thought by some that the deep trance - like state which deeply religious people claim to go into mimics this type of hypnosis, and the extremely strong and vivid impressions of the wounds and suffering are somehow transmitted from the mind to the body. This also fits with the fact that the Stigmata was first observed at around the time when graphic detail of the crucifiction started to apper in Christian art, making the wounds and suffering easier to comprehend and imagine in the minds of observers of the art.